A Cell Model Suitable for a High-Throughput Screening of Inhibitors of the Wnt/β-Catenin Pathway

A constitutive activation of the Wnt/β-catenin pathway is an initiating event in colon carcinogenesis. We developed colon cancer cells models that highlight the non-selectivity of previously described inhibitors of the Wnt pathway and we propose our model as a suitable screening system for inhibitor...

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Hoofdauteurs: Marina Grimaldi (Auteur), Abdelhay Boulahtouf (Auteur), Corinne Prévostel (Auteur), Alain Thierry (Auteur), Patrick Balaguer (Auteur), Philippe Blache (Auteur)
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Gepubliceerd in: Frontiers Media S.A., 2018-10-01T00:00:00Z.
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