Sodium valproate increases the brain isoform of glycogen phosphorylase: looking for a compensation mechanism in McArdle disease using a mouse primary skeletal-muscle culture in vitro

• Главные авторы: Noemí de Luna (Автор), Astrid Brull (Автор), Josep Maria Guiu (Автор), Alejandro Lucia (Автор), Miguel Angel Martin (Автор), Joaquin Arenas (Автор), Ramon Martí (Автор), Antoni L. Andreu (Автор), Tomàs Pinós (Автор)
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• Опубликовано: The Company of Biologists, 2015-05-01T00:00:00Z.
• Предметы: article
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McArdle disease, also termed 'glycogen storage disease type V', is a disorder of skeletal muscle carbohydrate metabolism caused by inherited deficiency of the muscle-specific isoform of glycogen phosphorylase (GP-MM). It is an autosomic recessive disorder that is caused by mutations in the...