Synthesis and in vitro and in vivo anti-inflammatory activity of novel 4-ferrocenylchroman-2-one derivatives

• Hoofdauteurs: Wei-Yun Guo (Auteur), Liu-Zeng Chen (Auteur), Bang-Nian Shen (Auteur), Xin-Hua Liu (Auteur), Guang-Ping Tai (Auteur), Qing-Shan Li (Auteur), Li Gao (Auteur), Ban-Feng Ruan (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

A series of novel 4-ferrocenylchroman-2-one derivatives were designed and synthesised to discover potent anti-inflammatory agents for treatment of arthritis. All the target compounds had been screened for their anti-inflammatory activity by evaluating the inhibition effect of LPS-induced NO producti...