Synthesis and in vitro and in vivo anti-inflammatory activity of novel 4-ferrocenylchroman-2-one derivatives

• Autors principals: Wei-Yun Guo (Autor), Liu-Zeng Chen (Autor), Bang-Nian Shen (Autor), Xin-Hua Liu (Autor), Guang-Ping Tai (Autor), Qing-Shan Li (Autor), Li Gao (Autor), Ban-Feng Ruan (Autor)
• Format: Llibre
• Publicat: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

A series of novel 4-ferrocenylchroman-2-one derivatives were designed and synthesised to discover potent anti-inflammatory agents for treatment of arthritis. All the target compounds had been screened for their anti-inflammatory activity by evaluating the inhibition effect of LPS-induced NO producti...