Design of Novel TRPA1 Agonists Based on Structure of Natural Vasodilator Carvacrol-In Vitro and In Silico Studies

• Hoofdauteurs: Đorđe Đukanović (Auteur), Relja Suručić (Auteur), Milica Gajić Bojić (Auteur), Saša M. Trailović (Auteur), Ranko Škrbić (Auteur), Žarko Gagić (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2024-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Considering the escalating global prevalence and the huge therapeutic demand for the treatment of hypertension, there is a persistent need to identify novel target sites for vasodilator action. This study aimed to investigate the role of TRPA1 channels in carvacrol-induced vasodilation and to design...