Design of Novel TRPA1 Agonists Based on Structure of Natural Vasodilator Carvacrol-In Vitro and In Silico Studies

• Egile Nagusiak: Đorđe Đukanović (Egilea), Relja Suručić (Egilea), Milica Gajić Bojić (Egilea), Saša M. Trailović (Egilea), Ranko Škrbić (Egilea), Žarko Gagić (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Considering the escalating global prevalence and the huge therapeutic demand for the treatment of hypertension, there is a persistent need to identify novel target sites for vasodilator action. This study aimed to investigate the role of TRPA1 channels in carvacrol-induced vasodilation and to design...