Application of biomimetic HPLC to estimate lipophilicity, protein and phospholipid binding of potential peptide therapeutics
Peptide therapeutics are new modalities offering several challenges to drug discovery. They are generally less stable and permeable in vivo. The characterization of their lipophilicity cannot be carried out using the traditional in silico or wet octanol/water partition coefficients. The prediction o...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
International Association of Physical Chemists (IAPC),
2018-06-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |