Inhibitory effect of THPGV-0 on the histamine release from antigen-induced RBL-2H3 cells

• Main Authors: Agung Endro Nugroho (Author), Ritmaleni Ritmaleni (Author), Novrizal Abdi Sahid (Author), Kazutaka Maeyama (Author)
• Format: Bog
• Udgivet: Universitas Gadjah Mada, 2010-10-01T00:00:00Z.
• Fag: article
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Tetrahydropentagamavunon-0 (THPGV-0) is assumed to be main metabolite product of biotransformation process of PGV-0. THPGV-0 was synthesized by converting PGV-0 to the compound by hydrogenation with Pd/C as a catalyst. PGV-0 potently inhibited the histamine release from rat mast cells in vitro and i...