Inhibitory effect of THPGV-0 on the histamine release from antigen-induced RBL-2H3 cells

• मुख्य लेखकों: Agung Endro Nugroho (लेखक), Ritmaleni Ritmaleni (लेखक), Novrizal Abdi Sahid (लेखक), Kazutaka Maeyama (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Universitas Gadjah Mada, 2010-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Tetrahydropentagamavunon-0 (THPGV-0) is assumed to be main metabolite product of biotransformation process of PGV-0. THPGV-0 was synthesized by converting PGV-0 to the compound by hydrogenation with Pd/C as a catalyst. PGV-0 potently inhibited the histamine release from rat mast cells in vitro and i...