Inhibitory effect of THPGV-0 on the histamine release from antigen-induced RBL-2H3 cells

• Autori principali: Agung Endro Nugroho (Autore), Ritmaleni Ritmaleni (Autore), Novrizal Abdi Sahid (Autore), Kazutaka Maeyama (Autore)
• Natura: Libro
• Pubblicazione: Universitas Gadjah Mada, 2010-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Tetrahydropentagamavunon-0 (THPGV-0) is assumed to be main metabolite product of biotransformation process of PGV-0. THPGV-0 was synthesized by converting PGV-0 to the compound by hydrogenation with Pd/C as a catalyst. PGV-0 potently inhibited the histamine release from rat mast cells in vitro and i...