Britanin relieves ferroptosis-mediated myocardial ischaemia/reperfusion damage by upregulating GPX4 through activation of AMPK/GSK3β/Nrf2 signalling

Context Ferroptosis was described as an important contributor to the myocardial ischaemia/reperfusion (MIR) injury, and britanin (Bri) was reported to exert antitumor and anti-inflammatory activities. Objective Our study explores the effect and mechanism of Bri on MIR damage. Materials and methods T...

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Príomhchruthaitheoirí: Haoyang Lu (Údar), Hui Xiao (Údar), Manyu Dai (Údar), Yangcheng Xue (Údar), Ren Zhao (Údar)
Formáid: LEABHAR
Foilsithe / Cruthaithe: Taylor & Francis Group, 2022-01-01T00:00:00Z.
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