Molecular properties, including chameleonicity, as essential tools for designing the next generation of oral beyond rule of five drugs

Background and Purpose. The classical drug discovery toolbox continually expands beyond traditional rule of five (Ro5)-compliant small molecules to include new chemical modalities for difficult-to-drug targets. The paper focuses on the molecular properties essential to drive oral bioavailability wit...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Giulia Caron (Auteur), Diego Garcia Jimenez (Auteur), Maura Vallaro (Auteur), Luigi Vitagliano (Auteur), Lucia Lopez Lopez (Auteur), Giulia Apprato (Auteur), Giuseppe Ermondi (Auteur)
Formaat: Boek
Gepubliceerd in: International Association of Physical Chemists (IAPC), 2024-08-01T00:00:00Z.
Onderwerpen:
Online toegang:Connect to this object online.
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Internet

Connect to this object online.

3rd Floor Main Library

Exemplaargegevens van 3rd Floor Main Library
Plaatsingsnummer: A1234.567
Kopie 1 Beschikbaar