Metformin therapy in a hyperandrogenic anovulatory mutant murine model with polycystic ovarian syndrome characteristics improves oocyte maturity during superovulation

• Glavni autori: Sabatini Mary E (Autor), Guo Lankai (Autor), Lynch Maureen P (Autor), Doyle Joseph O (Autor), Lee HoJoon (Autor), Rueda Bo R (Autor), Styer Aaron K (Autor)
• Format: Knjiga
• Izdano: BMC, 2011-05-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Metformin, an oral biguanide traditionally used for the treatment of type 2 diabetes, is widely used for the management of polycystic ovary syndrome (PCOS)-related anovulation. Because of the significant prevalence of insulin resista...