Preparation and evaluation of rotigotine-loaded implant for the treatment of Parkinson's disease and its evolution study
Purpose: To develop rotigotine-loaded implants (RI) to achieve continuous release of rotigotine for long duration for the treatment of Parkinson's disease (PD). Methods: RI was prepared by hot-melt extrusion method using poly (lactide-co-glycolide) (PLGA) as the matrix. In vitro drug release wa...
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Principais autores: | Aiping Wang (Autor), Yanxiang Liu (Autor), Rongcai Liang (Autor), Xuemei Zhang (Autor), Kaoxiang Sun (Autor), Zimei Wu (Autor), Wanhui Liu (Autor) |
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Formato: | Livro |
Publicado em: |
Elsevier,
2016-05-01T00:00:00Z.
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Acesso em linha: | Connect to this object online. |
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