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Preparation and evaluation of rotigotine-loaded implant for the treatment of Parkinson's disease and its evolution study

Purpose: To develop rotigotine-loaded implants (RI) to achieve continuous release of rotigotine for long duration for the treatment of Parkinson's disease (PD). Methods: RI was prepared by hot-melt extrusion method using poly (lactide-co-glycolide) (PLGA) as the matrix. In vitro drug release wa...

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Bibliographic Details
Main Authors:	Aiping Wang (Author), Yanxiang Liu (Author), Rongcai Liang (Author), Xuemei Zhang (Author), Kaoxiang Sun (Author), Zimei Wu (Author), Wanhui Liu (Author)
Format:	Book
Published:	Elsevier, 2016-05-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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