Impact of Pharmacokinetic and Pharmacodynamic Properties of Monoclonal Antibodies in the Management of Psoriasis

• প্রধান লেখক: Karine Rodríguez-Fernández (লেখক), Víctor Mangas-Sanjuán (লেখক), Matilde Merino-Sanjuán (লেখক), Antonio Martorell-Calatayud (লেখক), Almudena Mateu-Puchades (লেখক), Mónica Climente-Martí (লেখক), Elena Gras-Colomer (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2022-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The treatment of psoriasis has been revolutionized by the emergence of biological therapies. Monoclonal antibodies (mAb) generally have complex pharmacokinetic (PK) properties with nonlinear distribution and elimination. In recent years, several population pharmacokinetic/pharmacodynamic (PK/PD) mod...