Impact of Pharmacokinetic and Pharmacodynamic Properties of Monoclonal Antibodies in the Management of Psoriasis

• Main Authors: Karine Rodríguez-Fernández (Author), Víctor Mangas-Sanjuán (Author), Matilde Merino-Sanjuán (Author), Antonio Martorell-Calatayud (Author), Almudena Mateu-Puchades (Author), Mónica Climente-Martí (Author), Elena Gras-Colomer (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The treatment of psoriasis has been revolutionized by the emergence of biological therapies. Monoclonal antibodies (mAb) generally have complex pharmacokinetic (PK) properties with nonlinear distribution and elimination. In recent years, several population pharmacokinetic/pharmacodynamic (PK/PD) mod...