Impact of Pharmacokinetic and Pharmacodynamic Properties of Monoclonal Antibodies in the Management of Psoriasis

• Autores principales: Karine Rodríguez-Fernández (Autor), Víctor Mangas-Sanjuán (Autor), Matilde Merino-Sanjuán (Autor), Antonio Martorell-Calatayud (Autor), Almudena Mateu-Puchades (Autor), Mónica Climente-Martí (Autor), Elena Gras-Colomer (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2022-03-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The treatment of psoriasis has been revolutionized by the emergence of biological therapies. Monoclonal antibodies (mAb) generally have complex pharmacokinetic (PK) properties with nonlinear distribution and elimination. In recent years, several population pharmacokinetic/pharmacodynamic (PK/PD) mod...