Frequency of pharmacogenomic variants affecting efficacy and safety of anti-cancer drugs in a south Asian population from Sri Lanka

• मुख्य लेखकों: Priyanga Ranasinghe (लेखक), Nirmala Sirisena (लेखक), Thuwaragesh Vishnukanthan (लेखक), J. N. Ariadurai (लेखक), Sathsarani Thilakarathne (लेखक), C. D. Nelanka Priyadarshani (लेखक), D. P. Bhagya Hendalage (लेखक), Vajira H. W. Dissanayake (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2024-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Therapy with anti-cancer drugs remain the cornerstone of treating cancer. The effectiveness and safety of anti-cancer drugs vary significantly among individuals due to genetic factors influencing the drug response and metabolism. Data on the pharmacogenomic variations in Sri Lank...