Frequency of pharmacogenomic variants affecting efficacy and safety of anti-cancer drugs in a south Asian population from Sri Lanka

• Main Authors: Priyanga Ranasinghe (Author), Nirmala Sirisena (Author), Thuwaragesh Vishnukanthan (Author), J. N. Ariadurai (Author), Sathsarani Thilakarathne (Author), C. D. Nelanka Priyadarshani (Author), D. P. Bhagya Hendalage (Author), Vajira H. W. Dissanayake (Author)
• Format: Book
• Published: BMC, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Therapy with anti-cancer drugs remain the cornerstone of treating cancer. The effectiveness and safety of anti-cancer drugs vary significantly among individuals due to genetic factors influencing the drug response and metabolism. Data on the pharmacogenomic variations in Sri Lank...