An In Vivo Predictive Dissolution Methodology (iPD Methodology) with a BCS Class IIb Drug Can Predict the In Vivo Bioequivalence Results: Etoricoxib Products

The purpose of this study was to predict in vivo performance of three oral products of Etoricoxib (<i>Arcoxia</i><sup>®</sup> as reference and two generic formulations in development) by conducting in vivo predictive dissolution with GIS (Gastro Intestinal Simulator) and comp...

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Main Authors: Isabel Gonzalez-Alvarez (Author), Marival Bermejo (Author), Yasuhiro Tsume (Author), Alejandro Ruiz-Picazo (Author), Marta Gonzalez-Alvarez (Author), Bart Hens (Author), Alfredo Garcia-Arieta (Author), Greg E. Amidon (Author), Gordon L. Amidon (Author)
Format: Bog
Udgivet: MDPI AG, 2021-04-01T00:00:00Z.
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