An In Vivo Predictive Dissolution Methodology (iPD Methodology) with a BCS Class IIb Drug Can Predict the In Vivo Bioequivalence Results: Etoricoxib Products

• Auteurs principaux: Isabel Gonzalez-Alvarez (Auteur), Marival Bermejo (Auteur), Yasuhiro Tsume (Auteur), Alejandro Ruiz-Picazo (Auteur), Marta Gonzalez-Alvarez (Auteur), Bart Hens (Auteur), Alfredo Garcia-Arieta (Auteur), Greg E. Amidon (Auteur), Gordon L. Amidon (Auteur)
• Format: Livre
• Publié: MDPI AG, 2021-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The purpose of this study was to predict in vivo performance of three oral products of Etoricoxib (<i>Arcoxia</i>^® as reference and two generic formulations in development) by conducting in vivo predictive dissolution with GIS (Gastro Intestinal Simulator) and comp...