Potent carbonic anhydrase I, II, IX and XII inhibition activity of novel primary benzenesulfonamides incorporating bis-ureido moieties

• Үндсэн зохиолчид: Tuba Tekeli (Зохиогч), Suleyman Akocak (Зохиогч), Andrea Petreni (Зохиогч), Nebih Lolak (Зохиогч), Servet Çete (Зохиогч), Claudiu T. Supuran (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

A novel series of twelve aromatic bis-ureido-substituted benzenesulfonamides was synthesised by conjugation of aromatic aminobenzenesulfonamides with aromatic bis-isocyanates. The obtained bis-ureido-substituted derivatives were tested against four selected human carbonic anhydrase isoforms (hCA I,...