A Rho-kinase inhibitor reverses learning and memory deficits in a Rat model of chronic cerebral ischemia by altering Bcl-2/Bax-NMDAR signaling in the cerebral cortex

• Asıl Yazarlar: Ming Ni (Yazar), Jigang Zhang (Yazar), Lin Huang (Yazar), Gaolin Liu (Yazar), Qin Li (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2018-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The current study investigated whether a Rho-kinase inhibitor alleviated impairments in a rat model of chronic cerebral ischemia and examined the specific pathological mechanisms by which Rho-kinase impacts neuronal damage and cognitive dysfunction. Adult Sprague-Dawley rats underwent permanent bila...