Leonurine-Repressed miR-18a-5p/SOCS5/JAK2/STAT3 Axis Activity Disrupts CML malignancy

• প্রধান লেখক: Hui-Min Liu (লেখক), Chun-Ling Guo (লেখক), Yao-Fang Zhang (লেখক), Jian-Fang Chen (লেখক), Zhi-Peng Liang (লেখক), Lin-Hua Yang (লেখক), Yan-Ping Ma (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Leonurine, an active natural alkaloid compound isolated from Herba leonuri, has been reported to exhibit promising anticancer activity in solid tumors. The aim of this study was to explore whether leonurine is able to inhibit chronic myeloid leukemia (CML) malignancy. Here, we found that leonurine d...