Glyburide reduces bacterial dissemination in a mouse model of melioidosis.

• Główni autorzy: Gavin C K W Koh (Autor), Tassili A Weehuizen (Autor), Katrin Breitbach (Autor), Kathrin Krause (Autor), Hanna K de Jong (Autor), Liesbeth M Kager (Autor), Arjan J Hoogendijk (Autor), Antje Bast (Autor), Sharon J Peacock (Autor), Tom van der Poll (Autor), Ivo Steinmetz (Autor), W Joost Wiersinga (Autor)
• Format: Książka
• Wydane: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Burkholderia pseudomallei infection (melioidosis) is an important cause of community-acquired Gram-negative sepsis in Northeast Thailand, where it is associated with a ~40% mortality rate despite antimicrobial chemotherapy. We showed in a previous cohort study that patients taking glyburide ( = glib...