The KIT ligand KITLG promotes portal vein tumor thrombosis by up-regulating COL4A1 through STAT3-SMAD2 signaling in hepatocellular carcinoma

• Автори: Feifei Mao (Автор), Yuqiang Cheng (Автор), Kang Wang (Автор), Zongtao Chai (Автор), Lei Guo (Автор), Yanyan Xu (Автор), Xue Chen (Автор), Jie Shi (Автор), Weixing Guo (Автор), Junling Liu (Автор), Shuqun Cheng (Автор)
• Формат: Книга
• Опубліковано: Compuscript Ltd, 2024-06-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Portal vein tumor thrombosis (PVTT), a severe complication of hepatocellular carcinoma (HCC), markedly influences patient prognosis by fostering a hypercoagulable state. However, its molecular underpinnings remain largely unexplored. This study sheds light on the critical role of the KIT ligand (KIT...