Inhibition of tyrosinase activity and melanine pigmentation by 2-hydroxytyrosol

• Asıl Yazarlar: Ryuji Uchida (Yazar), Seiko Ishikawa (Yazar), Hiroshi Tomoda (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2014-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

2-Hydroxytyrosol (2-HT), originally reported as a synthetic compound, was isolated for the first time as a fungal metabolite. 2-HT was found to inhibit mushroom tyrosinase with an IC50 value of 13.0 µmol/L. Furthermore, 2-HT dose-dependently inhibited tyrosinase activity (IC50, 32.5 µmol/L) in the c...