Inhibition of tyrosinase activity and melanine pigmentation by 2-hydroxytyrosol

• Hoofdauteurs: Ryuji Uchida (Auteur), Seiko Ishikawa (Auteur), Hiroshi Tomoda (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2014-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

2-Hydroxytyrosol (2-HT), originally reported as a synthetic compound, was isolated for the first time as a fungal metabolite. 2-HT was found to inhibit mushroom tyrosinase with an IC50 value of 13.0 µmol/L. Furthermore, 2-HT dose-dependently inhibited tyrosinase activity (IC50, 32.5 µmol/L) in the c...