Combined use of phospholipid complexes and self-emulsifying microemulsions for improving the oral absorption of a BCS class IV compound, baicalin

• Autori principali: Huiyi Wu (Autore), Xiaoying Long (Autore), Fei Yuan (Autore), Li Chen (Autore), Sujing Pan (Autore), Yunjun Liu (Autore), Yoshiko Stowell (Autore), Xiaoling Li (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2014-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The aim of this study was to develop a formulation to improve the oral absorption of baicalin (BA) by combining a phospholipid complex (PC) and self-emulsifying microemulsion drug delivery system (SMEDDS), termed BA-PC-SMEDDS. BA-PC was prepared by a solvent evaporation method and evaluated by compl...