Combined use of phospholipid complexes and self-emulsifying microemulsions for improving the oral absorption of a BCS class IV compound, baicalin

• Main Authors: Huiyi Wu (Author), Xiaoying Long (Author), Fei Yuan (Author), Li Chen (Author), Sujing Pan (Author), Yunjun Liu (Author), Yoshiko Stowell (Author), Xiaoling Li (Author)
• Format: Book
• Published: Elsevier, 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to develop a formulation to improve the oral absorption of baicalin (BA) by combining a phospholipid complex (PC) and self-emulsifying microemulsion drug delivery system (SMEDDS), termed BA-PC-SMEDDS. BA-PC was prepared by a solvent evaporation method and evaluated by compl...