Prophylactic low-dose, bi-weekly benznidazole treatment fails to prevent Trypanosoma cruzi infection in dogs under intense transmission pressure.

• Auteurs principaux: Juan M Bustamante (Auteur), Angel M Padilla (Auteur), Brooke White (Auteur), Lisa D Auckland (Auteur), Rachel E Busselman (Auteur), Stephanie Collins (Auteur), Elizabeth L Malcolm (Auteur), Briana F Wilson (Auteur), Ashley B Saunders (Auteur), Sarah A Hamer (Auteur), Rick L Tarleton (Auteur)
• Format: Livre
• Publié: Public Library of Science (PLoS), 2022-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Trypanosoma cruzi naturally infects a wide variety of wild and domesticated mammals, in addition to humans. Depending on the infection dose and other factors, the acute infection can be life-threatening, and in all cases, the risk of chagasic heart disease is high in persistently infected hosts. Dom...