A Standardized Chemically Modified Curcuma longa Extract Modulates IRAK-MAPK Signaling in Inflammation and Potentiates Cytotoxicity

• Автори: Minakshi Rana (Автор), Preeti Maurya (Автор), Sukka Santosh Reddy (Автор), Vishal Singh (Автор), Hafsa Ahmad (Автор), Anil Kumar Dwivedi (Автор), Madhu Dikshit (Автор), Manoj Kumar Barthwal (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2016-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

The TLR/IL-1R pathway is a critical signaling module that is misregulated in pathologies like inflammation and cancer. Extracts from turmeric (Curcuma longa L.) enriched in curcumin and carbonyls like turmerones have been shown to exert potent anti-inflammatory effects. The present study evaluated t...