Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study

Cyclic imides containing 3-benzenesulfonamide, oxime, and β-phenylalanine derivatives were synthesised and evaluated to elucidate their in vivo anti-inflammatory and ulcerogenic activity and in vitro cytotoxic effects. Most active anti-inflammatory agents were subjected to in vitro COX-1/2 inhibitio...

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Main Authors: Alaa A.-M (Author), Adel S. El-Azab (Author), Nawaf A. AlSaif (Author), Mohammed M. Alanazi (Author), Manal A. El-Gendy (Author), Ahmad J. Obaidullah (Author), Hamad M. Alkahtani (Author), Abdulrahman A. Almehizia (Author), Ibrahim A. Al-Suwaidan (Author)
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出版: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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索引號: A1234.567
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