Cover Image

Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni.

The near exclusive use of praziquantel (PZQ) for treatment of human schistosomiasis has raised concerns about the possible emergence of drug-resistant schistosomes.We measured susceptibility to PZQ of isolates of Schistosoma mansoni obtained from patients from Kisumu, Kenya continuously exposed to i...

Full description

Saved in:

Bibliographic Details
Main Authors:	Sandra D Melman (Author), Michelle L Steinauer (Author), Charles Cunningham (Author), Laura S Kubatko (Author), Ibrahim N Mwangi (Author), Nirvana Barker Wynn (Author), Martin W Mutuku (Author), Diana M S Karanja (Author), Daniel G Colley (Author), Carla L Black (Author), William Evan Secor (Author), Gerald M Mkoji (Author), Eric S Loker (Author)
Format:	Book
Published:	Public Library of Science (PLoS), 2009-08-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

A genome sequence for Biomphalaria pfeifferi, the major vector snail for the human-infecting parasite Schistosoma mansoni.
by: Lijing Bu, et al.
Published: (2023)

Association of the gene polymorphisms IFN-gamma +874, IL-13 -1055 and IL-4 -590 with patterns of reinfection with Schistosoma mansoni.
by: Michael R Gatlin, et al.
Published: (2009)

Praziquantel treatment decreases Schistosoma mansoni genetic diversity in experimental infections.
by: Regina Coeli, et al.
Published: (2013)

Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model.
by: Nada Abla, et al.
Published: (2017)

Evaluation of morbidity in Schistosoma mansoni-positive primary and secondary school children after four years of mass drug administration of praziquantel in western Kenya
by: Bernard O. Abudho, et al.
Published: (2020)

Synergy of Omeprazole and Praziquantel In Vitro Treatment against Schistosoma mansoni Adult Worms.
by: Giulliana T Almeida, et al.
Published: (2015)

Efficacy of oxamniquine and praziquantel in the treatment of Schistosoma mansoni infection: a controlled trial
by: Ferrari M.L.A, et al.
Published: (2003)

Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure.
by: Paul McCusker, et al.
Published: (2021)

Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection.
by: Joseph Bertin Kadji Fassi, et al.
Published: (2022)

Effect of Dihydroartemisinin-Piperaquine on the Pharmacokinetics of Praziquantel for Treatment of <i>Schistosoma mansoni</i> Infection
by: Omary Mashiku Minzi, et al.
Published: (2021)

Effect of maternal Schistosoma mansoni infection and praziquantel treatment during pregnancy on Schistosoma mansoni infection and immune responsiveness among offspring at age five years.
by: Robert Tweyongyere, et al.
Published: (2013)

Transcriptomic responses of Biomphalaria pfeifferi to Schistosoma mansoni: Investigation of a neglected African snail that supports more S. mansoni transmission than any other snail species.
by: Sarah K Buddenborg, et al.
Published: (2017)

Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium.
by: Jean T Coulibaly, et al.
Published: (2012)

Evaluation of urine CCA assays for detection of Schistosoma mansoni infection in Western Kenya.
by: Hillary L Shane, et al.
Published: (2011)

The in vivo transcriptome of Schistosoma mansoni in the prominent vector species Biomphalaria pfeifferi with supporting observations from Biomphalaria glabrata.
by: Sarah K Buddenborg, et al.
Published: (2019)

Pathological and immunological evaluation of different regimens of praziquantel treatment in a mouse model of Schistosoma mansoni infection.
by: Ulrich Membe Femoe, et al.
Published: (2022)

Efficacy and Safety of Moxidectin, Synriam, Synriam-Praziquantel versus Praziquantel against Schistosoma haematobium and S. mansoni Infections: A Randomized, Exploratory Phase 2 Trial.
by: Beatrice Barda, et al.
Published: (2016)

Transcriptional responses of Biomphalaria pfeifferi and Schistosoma mansoni following exposure to niclosamide, with evidence for a synergistic effect on snails following exposure to both stressors.
by: Sarah K Buddenborg, et al.
Published: (2019)

Dynamics of serological responses to defined recombinant proteins during Schistosoma mansoni infection in mice before and after the treatment with praziquantel
by: Eman Sayed Mohammed, et al.
Published: (2020)

Observed reductions in Schistosoma mansoni transmission from large-scale administration of praziquantel in Uganda: a mathematical modelling study.
by: Michael D French, et al.
Published: (2010)

Dynamics of serological responses to defined recombinant proteins during Schistosoma mansoni infection in mice before and after the treatment with praziquantel.
by: Eman Sayed Mohammed, et al.
Published: (2020)

Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection.
by: Melissa C Sanchez, et al.
Published: (2017)

Diagnostic performance of Schistosoma real-time PCR in urine samples from Kenyan children infected with Schistosoma haematobium: day-to-day variation and follow-up after praziquantel treatment.
by: Natalie V S Vinkeles Melchers, et al.
Published: (2014)

Correction: Dynamics of serological responses to defined recombinant proteins during Schistosoma mansoni infection in mice before and after the treatment with praziquantel.
by: Eman Sayed Mohammed, et al.
Published: (2022)

Correction: Dynamics of serological responses to defined recombinant proteins during Schistosoma mansoni infection in mice before and after the treatment with praziquantel
by: Eman Sayed Mohammed, et al.
Published: (2022)

Efficacy and safety of praziquantel preventive chemotherapy in Schistosoma mansoni infected school children in Southern Ethiopia: A prospective cohort study
by: Tigist Dires Gebreyesus, et al.
Published: (2023)

Insufficiency of annual praziquantel treatment to control Schistosoma mansoni infections in adult women: A longitudinal cohort study in rural Tanzania.
by: Pallavi Mishra, et al.
Published: (2019)

Efeito do praziquantel incorporado a lipossomas nos diferentes estágios de desenvolvimento dos ovos de Schistosoma mansoni
by: T.F. Frezza, et al.
Published: (2007)

Cluster randomized trial comparing school-based mass drug administration schedules in areas of western Kenya with moderate initial prevalence of Schistosoma mansoni infections.
by: Diana M S Karanja, et al.
Published: (2017)

Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against Schistosoma haematobium: a randomized, exploratory, open-label trial.
by: Jennifer Keiser, et al.
Published: (2014)

Human IgG1 Responses to Surface Localised Schistosoma mansoni Ly6 Family Members Drop following Praziquantel Treatment.
by: Iain W Chalmers, et al.
Published: (2015)

Chlorination of Schistosoma mansoni cercariae.
by: Laura Braun, et al.
Published: (2020)

Schistosoma mansoni enhances host susceptibility to mucosal but not intravenous challenge by R5 Clade C SHIV.
by: Nagadenahalli B Siddappa, et al.
Published: (2011)

Influence of exposure history on the immunology and development of resistance to human Schistosomiasis mansoni.
by: Carla L Black, et al.
Published: (2010)

Genome-wide analysis of Schistosoma mansoni reveals limited population structure and possible praziquantel drug selection pressure within Ugandan hot-spot communities.
by: Tushabe John Vianney, et al.
Published: (2022)

Praziquantel decreases fecundity in Schistosoma mansoni adult worms that survive treatment: evidence from a laboratory life-history trade-offs selection study
by: Poppy H.L. Lamberton, et al.
Published: (2017)

Limited efficacy of repeated praziquantel treatment in Schistosoma mansoni infections as revealed by highly accurate diagnostics, PCR and UCP-LF CAA (RePST trial).
by: Pytsje T Hoekstra, et al.
Published: (2022)

Single Versus Double Dose Praziquantel Comparison on Efficacy and Schistosoma mansoni Re-Infection in Preschool-Age Children in Uganda: A Randomized Controlled Trial.
by: Allen Nalugwa, et al.
Published: (2015)

Schistosoma mansoni Infection Can Jeopardize the Duration of Protective Levels of Antibody Responses to Immunizations against Hepatitis B and Tetanus Toxoid.
by: Diana K Riner, et al.
Published: (2016)

Characterization of the phytochelatin synthase of Schistosoma mansoni.
by: Debalina Ray, et al.
Published: (2011)