Typing TREX1 gene in patients with systemic lupus erythematosus

• Main Authors: M. Fredi (Author), M. Bianchi (Author), L. Andreoli (Author), G. Greco (Author), I. Olivieri (Author), S. Orcesi (Author), E. Fazzi (Author), C. Cereda (Author), A. Tincani (Author)
• Format: Knjiga
• Izdano: PAGEPress Publications, 2015-06-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

An impaired expression of interferon-α regulated genes has been reported in patients with either systemic lupus erythematosus (SLE) or Aicardi-Goutières syndrome (AGS), a rare monogenic encephalopathy with onset in infancy. One of mutations causing AGS is located in the <em>TREX1</em> g...