Typing TREX1 gene in patients with systemic lupus erythematosus

• Autores principales: M. Fredi (Autor), M. Bianchi (Autor), L. Andreoli (Autor), G. Greco (Autor), I. Olivieri (Autor), S. Orcesi (Autor), E. Fazzi (Autor), C. Cereda (Autor), A. Tincani (Autor)
• Formato: Libro
• Publicado: PAGEPress Publications, 2015-06-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

An impaired expression of interferon-α regulated genes has been reported in patients with either systemic lupus erythematosus (SLE) or Aicardi-Goutières syndrome (AGS), a rare monogenic encephalopathy with onset in infancy. One of mutations causing AGS is located in the <em>TREX1</em> g...