Use of Heterologous Vesiculovirus G Proteins Circumvents the Humoral Anti-envelope Immunity in Lentivector-Based In Vivo Gene Delivery

• 主要な著者: Altar M. Munis (著者), Giada Mattiuzzo (著者), Emma M. Bentley (著者), Mary K. Collins (著者), James E. Eyles (著者), Yasuhiro Takeuchi (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2019-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Vesicular stomatitis virus Indiana strain glycoprotein (VSVind.G) mediates broad tissue tropism and efficient cellular uptake. Lentiviral vectors (LVs) are particularly promising, as they can efficiently transduce non-dividing cells and facilitate stable genomic transgene integration; therefore, LVs...