A single high-dose irradiation changes accumulation of methotrexate and gene expression levels of SLC and ABC transporters in cancer cells

• প্রধান লেখক: Kakeru Sato (লেখক), Tatsuya Seki (লেখক), Asuka Mizutani (লেখক), Yuka Muranaka (লেখক), Shiho Hirota (লেখক), Kodai Nishi (লেখক), Kana Yamazaki (লেখক), Ryuichi Nishii (লেখক), Takeo Nakanishi (লেখক), Ikumi Tamai (লেখক), Keiichi Kawai (লেখক), Masato Kobayashi (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Chemoradiotherapy is frequently used to treat cancer. Stereotactic body radiotherapy (SBRT) is a single high-dose radiotherapy used to treat a variety of cancers. The anticancer drug methotrexate (MTX) shows affinity for solute carrier (SLC) and ATP-binding cassette (ABC) transporters. This study in...