Germline variation of Ribonuclease H2 genes in ovarian cancer patients

Germline variation of Ribonuclease H2 genes in ovarian cancer patients

Abstract Epithelial ovarian carcinoma (EOC) is a genetically heterogeneous disease that is partly driven by molecular defects in mismatch repair (MMR) or homology-directed DNA repair (HDR). Ribonuclease H2 serves to remove mis-incorporated ribonucleotides from DNA which alleviates HDR mechanisms and...

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Main Authors: Rahel Polaczek (Author), Peter Schürmann (Author), Lisa-Marie Speith (Author), Robert Geffers (Author), Matthias Dürst (Author), Peter Hillemanns (Author), Tjoung-Wo (Author), Clemens Liebrich (Author), Thilo Dörk (Author)
Format: Book
Published: BMC, 2020-12-01T00:00:00Z.
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3rd Floor Main Library

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