SUMOylation of pregnane X receptor suppresses rifampicin-induced CYP3A4 and P-gp expression and activity in LS174T cells
The pregnane X receptor (PXR) has been well-established as a critical mediator in regulating important drug metabolizing enzymes and transporter proteins, including cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp). Previous studies identified that PXR served as a molecular target of SUMOylatio...
Uloženo v:
Hlavní autoři: | , , , , , , , , , , |
---|---|
Médium: | Kniha |
Vydáno: |
Elsevier,
2016-02-01T00:00:00Z.
|
Témata: | |
On-line přístup: | Connect to this object online. |
Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
Internet
Connect to this object online.3rd Floor Main Library
Signatura: |
A1234.567 |
---|---|
Jednotka 1 | Dostupné |