Adipose Stromal Cell-Secretome Counteracts Profibrotic Signals From IPF Lung Matrices

• Main Authors: Gwenda F. Vasse (Author), Lisette Van Os (Author), Marina De Jager (Author), Marnix R. Jonker (Author), Theo Borghuis (Author), L. Tim Van Den Toorn (Author), Pytrick Jellema (Author), Eric S. White (Author), Patrick Van Rijn (Author), Martin C. Harmsen (Author), Irene H. Heijink (Author), Barbro N. Melgert (Author), Janette K. Burgess (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease characterized by excess deposition and altered structure of extracellular matrix (ECM) in the lungs. The fibrotic ECM is paramount in directing resident cells toward a profibrotic phenotype. Collagens, an important part of...