Preparation and Characterization of a Novel Swellable and Floating Gastroretentive Drug Delivery System (<i>sf</i>GRDDS) for Enhanced Oral Bioavailability of Nilotinib

• Những tác giả chính: Hong-Liang Lin (Tác giả), Ling-Chun Chen (Tác giả), Wen-Ting Cheng (Tác giả), Wei-Jie Cheng (Tác giả), Hsiu-O Ho (Tác giả), Ming-Thau Sheu (Tác giả)
• Định dạng: Sách
• Được phát hành: MDPI AG, 2020-02-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Regarding compliance and minimization of side effects of nilotinib therapy, there is a medical need to have a gastroretentive drug delivery system (GRDDS) to enhance the oral bioavailability that is able to administer an optimal dose in a quaque die (QD) or daily manner. In this study, the influence...