Preparation and Characterization of a Novel Swellable and Floating Gastroretentive Drug Delivery System (<i>sf</i>GRDDS) for Enhanced Oral Bioavailability of Nilotinib

• Κύριοι συγγραφείς: Hong-Liang Lin (Συγγραφέας), Ling-Chun Chen (Συγγραφέας), Wen-Ting Cheng (Συγγραφέας), Wei-Jie Cheng (Συγγραφέας), Hsiu-O Ho (Συγγραφέας), Ming-Thau Sheu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2020-02-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Regarding compliance and minimization of side effects of nilotinib therapy, there is a medical need to have a gastroretentive drug delivery system (GRDDS) to enhance the oral bioavailability that is able to administer an optimal dose in a quaque die (QD) or daily manner. In this study, the influence...