Preparation and Characterization of a Novel Swellable and Floating Gastroretentive Drug Delivery System (<i>sf</i>GRDDS) for Enhanced Oral Bioavailability of Nilotinib

• Main Authors: Hong-Liang Lin (Author), Ling-Chun Chen (Author), Wen-Ting Cheng (Author), Wei-Jie Cheng (Author), Hsiu-O Ho (Author), Ming-Thau Sheu (Author)
• Format: Book
• Published: MDPI AG, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Regarding compliance and minimization of side effects of nilotinib therapy, there is a medical need to have a gastroretentive drug delivery system (GRDDS) to enhance the oral bioavailability that is able to administer an optimal dose in a quaque die (QD) or daily manner. In this study, the influence...