The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines

• Những tác giả chính: Stefan Landgraeber (Tác giả), Marcus Jäger (Tác giả), Joshua J. Jacobs (Tác giả), Nadim James Hallab (Tác giả)
• Định dạng: Sách
• Được phát hành: Hindawi Limited, 2014-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

All of the over 1 million total joint replacements implanted in the US each year are expected to eventually fail after 15-25 years of use, due to slow progressive subtle inflammation at the bone implant interface. This inflammatory disease state is caused by implant debris acting, primarily, on inna...