A mitotic recombination map proximal to the <it>APC </it>locus on chromosome 5q and assessment of influences on colorectal cancer risk

• Главные авторы: Clark Susan (Автор), Guenther Thomas (Автор), Spain Sarah (Автор), Jones Angela (Автор), Rowan Andrew (Автор), Harvey John J (Автор), Schaschl Helmut (Автор), Teixeira Ana (Автор), Winter Eitan (Автор), Ranta Susanna (Автор), Howarth Kimberley (Автор), Stewart Aengus (Автор), Silver Andrew (Автор), Tomlinson Ian (Автор)
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• Опубликовано: BMC, 2009-06-01T00:00:00Z.
• Предметы: article
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<p>Abstract</p> <p>Background</p> <p>Mitotic recombination is important for inactivating tumour suppressor genes by copy-neutral loss of heterozygosity (LOH). Although meiotic recombination maps are plentiful, little is known about mitotic recombination. The <it>A...