A mitotic recombination map proximal to the <it>APC </it>locus on chromosome 5q and assessment of influences on colorectal cancer risk

• Main Authors: Clark Susan (Author), Guenther Thomas (Author), Spain Sarah (Author), Jones Angela (Author), Rowan Andrew (Author), Harvey John J (Author), Schaschl Helmut (Author), Teixeira Ana (Author), Winter Eitan (Author), Ranta Susanna (Author), Howarth Kimberley (Author), Stewart Aengus (Author), Silver Andrew (Author), Tomlinson Ian (Author)
• Format: Book
• Published: BMC, 2009-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Mitotic recombination is important for inactivating tumour suppressor genes by copy-neutral loss of heterozygosity (LOH). Although meiotic recombination maps are plentiful, little is known about mitotic recombination. The <it>A...