Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase

• المؤلفون الرئيسيون: Dres Damgaard (مؤلف), Mads Emil Bjørn (مؤلف), Peter Østrup Jensen (مؤلف), Claus Henrik Nielsen (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Protein citrullination catalysed by peptidylarginine deiminase (PAD) may play an important pathogenic role in several chronic inflammatory diseases and malignancies. PAD2, PAD4, and citrullinated proteins are found in the synovium of rheumatoid arthritis patients. PAD activity is dependent on calciu...