Spontaneous Physical Activity Downregulates Pax7 in Cancer Cachexia

• मुख्य लेखकों: Dario Coletti (लेखक), Paola Aulino (लेखक), Eva Pigna (लेखक), Fabio Barteri (लेखक), Viviana Moresi (लेखक), Daniela Annibali (लेखक), Sergio Adamo (लेखक), Emanuele Berardi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2016-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Emerging evidence suggests that the muscle microenvironment plays a prominent role in cancer cachexia. We recently showed that NF-kB-induced Pax7 overexpression impairs the myogenic potential of muscle precursors in cachectic mice, suggesting that lowering Pax7 expression may be beneficial in cancer...