Self-microemulsifying drug delivery system for improving the bioavailability of huperzine A by lymphatic uptake

• Päätekijät: Fang Li (Tekijä), Rongfeng Hu (Tekijä), Bin Wang (Tekijä), Yun Gui (Tekijä), Gang Cheng (Tekijä), Song Gao (Tekijä), Lei Ye (Tekijä), Jihui Tang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2017-05-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Huperzine A (Hup-A) is a poorly water-soluble drug with low oral bioavailability. A self-microemulsifying drug delivery system (SMEDDS) was used to enhance the oral bioavailability and lymphatic uptake and transport of Hup-A. A single-pass intestinal perfusion (SPIP) technique and a chylomicron flow...