Protective Effect of Tempol on Acute Kidney Injury Through PI3K/Akt/Nrf2 Signaling Pathway

• Hoofdauteurs: Gensheng Zhang (Auteur), Qiaoling Wang (Auteur), Qin Zhou (Auteur), Renjun Wang (Auteur), Minze Xu (Auteur), Huiping Wang (Auteur), Lei Wang (Auteur), Christopher S. Wilcox (Auteur), Ruisheng Liu (Auteur), En Yin Lai (Auteur)
• Formaat: Boek
• Gepubliceerd in: Karger Publishers, 2016-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background/Aims: Tempol is a protective antioxidant against ischemic injury in many animal models. The molecular mechanisms are not well understood. Nuclear factor erythroid 2-related factor (Nrf2) is a master transcription factor during oxidative stress, which is enhanced by activation of protein k...