Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and IGF-1R

• मुख्य लेखकों: Cornelius Hempel (लेखक), Frank Totzke (लेखक), Christoph Schächtele (लेखक), Abdulkarim Najjar (लेखक), Wolfgang Sippl (लेखक), Christoph Ritter (लेखक), Andreas Hilgeroth (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Novel 4-benzylamino benzo-anellated pyrrolo[2,3-b]pyridines have been synthesized with varied substitution patterns both at the molecular scaffold of the benzo-anellated ring and at the 4-benzylamino residue. With a structural similarity to substituted thieno[2,3-d]pyrimidines as epidermal growth fa...